Extended Data Fig. 6: Molecular Dynamics (MD) simulations of unbound mouse IL-12, human IL-12 and human IL-23.
From: Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23
Structures of mouse IL-12 (a), human IL-12 (b) and human IL-23 (c), averaged over three replicate 300 ns MD runs, are shown as cartoons colored according to the average root mean square fluctuations (r.m.s.f.) of backbone atom positions over the combined MD trajectory. The thickness of the cartoon loop radius corresponds to the local r.m.s.f. value.
