Extended Data Fig. 1: Effects of Khc tail truncations on motor association with microtubules.
From: Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport
Frequency of all microtubule (MT)-binding events (processive, static and diffusive) for Khc FL, Khc910, Khc940 and KhcΔAMB with or without Tm1 FL. For all plots, mean ± s.d. is shown and is derived from 16-59 microtubules (N) from 4–15 imaging chambers and 2–5 independent experiments (n) per condition (see Supplementary Table 1). Mean values for each independent experiment (large dots) are superimposed on values for individual microtubules (small dots). Black or white circles indicate presence or absence of indicated components, respectively. Parallel experiments are shown with large dots of the same color. Cy3-osk 3′ UTR was included in all experiments. Statistical significance was determined by unpaired two-tailed t-tests using N values (total number of microtubules). ns: not significant (p > 0.05).
