Fig. 2: Cryo-EM maps of the Commander complex. | Nature Structural & Molecular Biology

Fig. 2: Cryo-EM maps of the Commander complex.

From: Structure and interactions of the endogenous human Commander complex

Fig. 2

a,b, Cryo-EM maps of the Commander complex COMMD-ring from native (gray) (a) and from crosslinked (gold) (b) samples. The insets show the I-coil region from both maps at lower isosurface threshold. c, Focused cryo-EM density map with DENND10 and CCDC22/93 coiled coils (focused map 1). d, Focused cryo-EM density map with Retriever subregion (focused map 2). e, A composite map of the complete Commander complex. f, Same as in e, rotated 90° around the x axis as indicated. The inset shows the structural detail of the map from within the COMMD-ring.

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