Fig. 5: NC interactions with TF.
From: Resolving chaperone-assisted protein folding on the ribosome at the peptide level
a, Structure of E. coli TF (PDB 1W26). RBD, ribosome binding domain; SBD, substrate binding domain; PPD, peptidyl-prolyl isomerase domain. The ribosome binding motif in the RBD is indicated with a red dashed rectangle. b, Difference in deuterium uptake between isolated TF and TF bound to DHFR RNCs after 10 s deuteration. Darker blue indicates less deuteration of RNC-bound TF relative to isolated TF (increasing protection). The sites on arm 2 that preferentially engage 1–126RNC are marked by ellipses. See also Supplementary Data 1. c, TF surface colored according to hydrophobicity75.
