Extended Data Fig. 2: Overview of cryo-EM processing of human SPG11-SPG15.
From: Structural basis for membrane remodeling by the AP5–SPG11–SPG15 complex
a, Coomassie blue-stained SDS-PAGE of purified SPG11-SPG15. SDS-PAGE is representative of at least three independent experiments. MW, molecular weight. b, Representative motion-corrected cryo-EM micrograph (of 33,954 micrographs from 4 datasets) of the human SPG11-SPG15 complex. c, Representative 2D class averages for the SPG11-SPG15 complex. d, Flow chart of cryo-EM data processing. e, SPG11-SPG15 map color-coded by the local resolution estimation.
