Fig. 3: Structures of the PP2A:B55–p107 and PP2A:B55–Eya3 complexes.
From: Cryo-EM structures of PP2A:B55 with p107 and Eya3 define substrate recruitment
a, Cryo-EM map and model of PP2A:B55–p107. Two views of the map (top) are shown with the corresponding view of the molecular model (bottom). b, Cryo-EM map and model of PP2A:B55–Eya3. c, Overlay of p107 (salmon) and Eya3 (dark magenta) bound to PP2A:B55 (PP2A colored as in Fig. 1a). d, Close-up view of p107 and Eya3 bound to B55, with interacting residues shown as sticks. Key interacting pockets on B55 are labeled and colored (pockets in the platform, beige; pockets in the wall, green). e, Same as d, but only p107 and Eya3 are shown with the N-terminal and C-terminal residues labeled.
