Extended Data Fig. 1: p107 binds PP2A:B55 – NMR data.
From: Cryo-EM structures of PP2A:B55 with p107 and Eya3 define substrate recruitment
a. 2D [1H,15N] HSQC spectrum of 15N-labeled p107589-731 (black) and p107612-687 (green). N- and C-terminal peaks of p107612-687 are labeled, highlighting that only these peaks show small chemical shift changes. b. 2D [1H,15N] HSQC spectrum of 15N-labeled p107589-731 with (pink) and without (black) PP2A:B55. Significant number of peaks are pink, corresponding to unbound p107 residues. c. 2D [1H,15N] HSQC spectrum of 15N-labeled p107589-731 with (pink), without (black) PP2A:B55 and p107612-687 (green), highlighting that most black peaks in (b) correspond with green peaks from optimized p107612-687.
