Extended Data Fig. 1: TSS reannotation.
From: Evolution of promoter-proximal pausing enabled a new layer of transcription control
PRO-seq (blue) and PRO-cap24 (red) metaprofiles for S. Pombe10 (a), S. cerevisiae10 (b), D. Melanogaster24 (c), and H. Sapiens98 (d). Upper panels use published gene annotations, lower panels use reannotated genes. Note the relative depletion of PRO-cap reads upstream and downstream of the TSS and more focused pause in PRO-seq signal of D. melanogaster and H. sapiens in re annotated panels.
