Extended Data Fig. 3: Association of NELF and HEXIM subunits with pausing.
From: Evolution of promoter-proximal pausing enabled a new layer of transcription control
Box and whiskers plots show pausing index values in each species. Samples are clustered by the presence (n = 12) or absence (n = 8) of any NELF subunits (a), and presence () or absence () of HEXIM subunits (b). A two-sided Mann-Whitney test was used to compute p-values. Boxplot whiskers extend from the first/third quartile to the minima/maxima, ignoring outliers, while horizontal lines denote the median.(c) Box and whiskers plot of pausing indexes in each species. Boxes are clustered by which NELF subunits are present in each species for which PRO-seq (n = 11), GRO-seq (n = 2), and ChRO-seq (n = 6), were used in this project. Boxplot whiskers extend from the first/third quartile to the minima/maxima, ignoring outliers, while horizontal lines denote the median.
