Extended Data Fig. 3: Intact, denatured LC-MS deconvoluted spectra of DRT1.
From: Semirandom DNA adducts regulate a filamentous defense-associated reverse transcriptase
a) DRT1wt, and b) DRT1RTKO. DRT1wt shows the addition of mass of approximately 312 Da, consistent with deoxyadenosine monophosphate (313 Da) addition. c) Reverse phase base peak traces of DRT1wt tryptic digest with extracted ion chromatogram highlighting deoxyadenosine [dA]-containing peptides. Extracted ion chromatograms of the peptide INEIQNEVGTSSIPER ( + 3 charge state) with 1–4 deoxyadenosines showing sequential elution of the single dA-bound species eluting first, followed by the sequential elution of each +1[dA] species.
