Table 1 Synopsis of the e-Phys toolbox and the tools that can be used for LFP analysis.

From: Integrated open-source software for multiscale electrophysiology

e-PHYS TOOLBOX

Acquisition Systems

Blackrock (.nsX), Ripple (.nsX), Plexon (.plx, .pl2), Intan (.rhd, .rhs), Neurodata without borders (.nwb), Tucker Davis Technologies

Spike Sorters

WaveClus, UltraMegaSort2000, Kilosort (Klusters)

LFP spectral Artifact Removal

Bayesian spectral spiking-artifact removal

Spike-related Functions

Tuning Curves, Raster Plots, PSTH, Spike Field Coherence, Spike triggered Average

LFP - ANALYSIS

Pre-processing

DC-offset removal, Band-pass/band-stop/notch filtering, resampling

Artifact Removal

SSP, ICA

Frequency

FFT, Welch Density, Morlet Wavelets, Hilbert transform, Multi-tapers, Phase Amplitude Coupling, Instantaneous frequency, Canolty Maps

Connectivity

Correlation, coherence, Bivariate Granger causality, Phase Locking Value, Amplitude Envelope Correlation, Phase Transfer Entropy

Statistics and machine learning

Parametric testing (zero/baseline), Partial Least Squares, Support Vector Machine classification, Linear Discriminant Analysis classification

  1. The e-Phys toolbox provides a working framework for every step of the e-Phys analysis and each module can easily be enriched with future additions.
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