Fig. 5

Reproducibility of biological replicates in RRBS and RNA-seq data sets. (a,b) Pearson correlation and hierarchical clustering of DNA methylation profiles (union CpGs across whole genome) and gene expression profiles. FC, FH, AMC, AMH, AFC, and AFH represent fetal control, fetal hypoxia, adult male control, adult male hypoxia, adult female control and adult female hypoxia. PCA of gene expression profiles in fetal rat heart (c,d) DNA methylation profiles in promoter region across all genes in adult male rat heart.