Table 3 Top colocalized genes as inferred between meta-analysis eQTL and the PGC2 schizophrenia GWAS.
Gene | eQTL Peak Location* | NSNPs | Min(p-value) | Best Colocalized SNP** | Posterior Probability of Colocalization | Additional Candidates at this Locus*** | |||
|---|---|---|---|---|---|---|---|---|---|
Chr | Start | End | GWAS | eQTL | |||||
RERE | 1 | 7412645 | 9877280 | 4905 | 2.72E-09 | 2.28E-21 | rs301792 | 0.730 | |
PTPRU | 1 | 28563084 | 30653243 | 4099 | 1.28E-09 | 4.42E-10 | rs1498232 | 0.890 | |
FOXN2 | 2 | 47542228 | 49606348 | 5437 | 1.66E-06 | 8.85E-45 | rs79073127 | 0.782 | |
C3orf49 | 3 | 62805378 | 64834213 | 4906 | 2.58E-08 | 1.10E-13 | rs832187 | 0.820 | Yes |
THOC7 | 3 | 62819766 | 64848612 | 4886 | 2.58E-08 | 2.21E-39 | rs832190 | 0.943 | Yes |
TBC1D19 | 4 | 25578209 | 27755954 | 4432 | 7.44E-07 | 7.85E-07 | rs6825268 | 0.900 | |
CLCN3 | 4 | 169533866 | 171644821 | 4956 | 1.02E-08 | 1.91E-09 | rs10520163 | 0.768 | |
PPP1R18 | 6 | 29644275 | 31655438 | 1055 | 1.16E-19 | 5.52E-07 | rs2523607 | 0.827 | Yes |
LINC00222 | 6 | 108073451 | 110091064 | 3600 | 3.37E-08 | 1.63E-07 | rs9398171 | 0.852 | |
FAM85B | 8 | 8089567 | 9084121 | 3725 | 2.03E-08 | 5.63E-31 | rs2980439 | 0.948 | Yes |
ENDOG | 9 | 130581300 | 132584048 | 3294 | 1.92E-06 | 6.90E-62 | rs6478854 | 0.721 | Yes |
RP11-677M14.2 | 11 | 123614560 | 125616016 | 5253 | 3.68E-12 | 1.50E-09 | rs55661361 | 0.975 | |
FURIN | 15 | 90414642 | 92426654 | 4767 | 2.30E-12 | 1.29E-20 | rs4702 | 0.999 | |
CNOT1 | 16 | 57553885 | 59662867 | 5364 | 1.15E-08 | 1.16E-06 | rs12325245 | 0.862 | |
ELAC2 | 17 | 11896953 | 13921426 | 5651 | 2.84E-06 | 3.90E-106 | rs1044564 | 0.856 | |
ZNF823 | 19 | 10832190 | 12840037 | 3844 | 1.57E-06 | 5.38E-10 | rs3095917 | 0.961 | |
PTK6 | 20 | 61160251 | 62960229 | 4527 | 4.03E-08 | 1.09E-26 | rs427230 | 0.897 | |
