Table 3 Review of experimental stages and the respective available data sets*.

Experimental stage number	Experimental stage
state1	Isoflurane	P_728, P_737, P_738, P_739, P_743, P_746, P_749, P_752, P_753, P_791, P_794
*state2*	Fentanyl	P_728, P_737, P_738, P_739, P_743, P_746, P_749, P_752, P_753, P_791, P_794
state2.5	90 min post-fentanyl	P_739, P_753
state3	Propofol	P_728, P_737, P_738, P_743, P_746, P_752
state4	Moderate sedation - immediate measurement	P_728, P_737, P_738, P_743, P_746, P_752
state5	60 min post-moderate sedation	P_737, P_743, P_746, P_752
state5.5	Fentanyl directly pre-ischemia	P_794
state6	1^st ischemic phase: gradual ischemia	P_738, P_739, P_746, P_749, P_752, P_753
state 7a^#	15 min recovery post-ischemia (first period)	P_739, P_746, P_749, P_752, P_753, P_791, P_794
state 7b^#	30 min recovery post-ischemia (first period)	P_746, P_749, P_752, P_753, P_791, P_794
state8	2^nd ischemic phase: gradual ischemia	P_739, *P_746, P_752, P_753*, P_791, P_794
state9	15 min recovery post-ischemia	P_737, P_743 (after single ischemia period); P_739, P_746, P_749, P_752, P_753, P_791, P_794 (after second ischemia period)
state10	30 min recovery post-ischemia	P_746, P_749, P_752, P_753, P_791, P_794
state11	45 min recovery post-ischemia	P_737, P_739, P_743, P_749, P_752, P_753, P_791, P_794
state12	60 min recovery post-ischemia	P_737, P_743, P_749, P_752, P_753, P_791, P_794

Bold font: animals and states selected for the analyses presented in the Technical validation section.
^#the recordings of the state 7 are available at 100 Hz sampling rate, rather than 2000 Hz as all other states; all recordings are provided in 5 min duration.
*for these animals, at 1^st and 2^nd stages of ischemia we provided 5 min files - in keeping with the rest of the dataset - representing the final stage of each ischemia episode. Details including any artifacts observed, for each file and for each channel, are provided in the auxiliary spreadsheet, also available on FigShare¹⁷.

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