Fig. 5

Functional enrichment analysis of progesterone-independent PRA and PRB interacting partners by IPA. (a) Venn diagram indicating the number of PRA and PRB interacting proteins both total, common, and unique interactors of PRA and PRB. (b) Total candidate interacting partners of PRA&PRB, common PRA&PRB, and (c) only unique-PRA interacting partners were used to predict the functional enrichment analysis. The vertical axis (y-axis) corresponds to the functional annotations. The horizontal axis (x-axis) corresponds to the enrichment score (-log10 p-value) based on the Fisher’s exact test (p-value < 0.05), the dash line indicates the minimum significance level (p-value < 0.05). Activation state (z-score) was indicated in color scale between −4.5 to 4.5, red color indicates negative z-score and blue color indicates positive z-score.