Table 1 Some tract-tracer substances and factors which are axonally transported or propagated by diffusion.
Tracer family | Examples | Dir | Vel | Pub |
|---|---|---|---|---|
Proteins | Horseradish peroxidase (HRP) | R/A | F | |
Albumin | ||||
Immunoglobulin M (IgM) | R | |||
Anorganic fluorochromes | Fast Blue (FB) | R | M | |
Diamidino yellow (DY) | R | |||
Fluoro-gold (FG) | R | |||
Dextranes | Fluoro-Ruby (FR) | A/R | M | |
Biotinylated dextran amine (BDA) | A/R | |||
Lectines | Wheat germ agglutinin (WGA; WGA-HRP) | R/A | F | |
Bandeiraea simplicifolia isolectin B4 (IB4) | A | |||
Phaseolus vulgaris-leucoagglutinin (PHA-L) | A | |||
Beads | Latex microspheres | R | F | |
Cholera toxin B-gold | R | |||
Wheat germ agglutinin-apoHRP gold | R | |||
Bacterial toxins | Tetanus toxin fragment C (BIIb) | R/A | F | |
Botulinum toxin A (BoTu) | R/A | |||
Cholera toxin B fragment (CTB) | R/A | |||
Growth factors | Nerve growth factor (NGF) | R | F | |
Glial cell-derived neurotrophic factor (GDNF) | A | |||
Ciliary neurotrophic factor (CNTF) | R | |||
Amino acids | 3H-Leucin | A | F/S | |
3H-Prolin | A | F/S | ||
Vit. biotin and L-lysine | Biocytin | A | F | |
Carbocyanine dyes | DiI | A/R | S | |
DiO | A/R | S |
