Table 3 Key fields in the immune signature data model for a gene expression signature.
From: A curated collection of human vaccination response signatures
Column name | Ontology | Values |
|---|---|---|
response_component | HGNC | STAT1, IRF9, SPI1, CD74, HLA-E, TNFSF13B |
tissue_type | Cell Ontology | CL:2000001 (peripheral blood mononuclear cell) |
exposure_material | Vaccine Ontology | VO:0000045 (Fluarix); VO:0000046 (Fluvirin) |
target_pathogen | NCBI Taxonomy | 504904 (Influenza A virus (A/Brisbane/59/2007(H1N1))); 476294 (Influenza A virus (A/Brisbane/10/2007(H3N2))); 461739 (Influenza B virus (B/Florida/4/2006)) |
vaccine_year | 2008 | |
time_point | 1 | |
time_point_units | days | |
baseline_time_event | time of vaccination (first dose) | |
cohort | subgroup high responders | |
publication_reference (PMID) | 21357945 | |
comparison | correlated with titer response index (TRI) | |
response_behavior | positive |
