Fig. 1 | Scientific Data

Fig. 1

From: NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency

Fig. 1

NeuroLINCS project overview. (a) Omic data generation centers include transcriptomics, proteomics, epigenomics, robotic imaging assays and cell-based functional studies. Molecular signatures of disease from epigenetic, RNA and protein analyses are incorporated into integrative network analysis using Omic Integrator. (b) Samples generated from 12 patient-derived hiPSC lines. Proteomics data is generated using DIA-MS methods on TripleTOFs (Sciex) and searched using sample specific peptide spectral libraries generated from DIA-MS of pooled samples. Analyte signals are extracted using OpenSWATH and MapDIA as specified.

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