Table 1 Overview of Immune Signatures Data Resource Study Participants Metadata.

From: The Immune Signatures data resource, a compendium of systems vaccinology datasets

Study Accession

Pathogen (Vaccine Type)

Number of Participants

Number of Samples

Vaccine

Adjuvant

Race

Ethnicity

Cohort

Matrix

Pubmed ID

Geographical Location

SDY1373

Ebola47 (Recombinant Viral Vector)

13

46

UKE Phase I rVSV ZEBOV

VSV

Not Specified

Not Specified

dose 20 × 10^6 ofu,dose 3 × 10^6 pfu

SDY1373_WholeBlood_highDose_Geo,SDY1373_WholeBlood_lowDose_Geo

28854372

Metropolitan France

SDY1328

Hepatitis A/B48 (Inactivated/Recombinant protein)

164

325

Twinrix

None

White

Not Hispanic or Latino

healthy adults

SDY1328_WholeBlood_HealthyAldults_Geo

26742691

Canada

SDY1291

HIV49 (Recombinant Viral Vector)

10

50

Ad5/HIV

AdV

White, Black, or African American

Not Hispanic or Latino

healthy HIV-1-uninfected adults

SDY1291_PBMC_HealthyHIVUninfected_Geo

23151505

US: Washington

SDY1119

Influenza22 (Inactivated)

72

177

TIV (2011)

None

Not Specified

Not Specified

young and old type 2 diabetes cohorts

SDY1119_PBMC_youngT2D_Geo, SDY1119_PBMC_youngHealthy_Geo,SDY1119_PBMC_oldHealthy_Geo,SDY1119_PBMC_oldT2D_Geo

26682988

US: Georgia

SDY1276

Influenza50 (Inactivated)

218

828

TIV (2008)

None

Not Specified

Not Specified

Validation Cohort; Females 2008-2009 trivalent influenza vaccine,Discovery Cohort; Males 2008?2009 trivalent influenza vaccine

SDY1276_WholeBlood_Validation_Geo,SDY1276_WholeBlood_Discovery_Geo

21357945

US: Texas

SDY180

Influenza51 (Inactivated)

12

102

TIV (2009)

None

Asian,Whit e,Black or African American

Not Hispanic or Latino

Study group 2 2009-2010 Fluzone,Study group 1 2009-2010 Fluzone

SDY180_WholeBlood_Grp2Fluzone_G eo,SDY180_WholeBlood_Grp1Fluzone_Geo

23601689

US: Texas

SDY212

Influenza52 (Inactivated)

90

90

TIV (2008)

None

Oth er,Wh ite,As ian,American I,ndian or Alaska Native

Not Hispanic or L atino,Hispanic or Latino

Cohort_1,Cohort_2

SDY212_WholeBlood_Young_Geo,SDY212_PBMC_Young_geo,SDY212_WholeBlood_Older_Geo,SDY212_PBMC_Older_Geo

23591775

US: California

SDY224

Influenza53 (Inactivated)

5

55

TIV (2010)

None

White,Black or African American,American Indian or Alaska Native

Not Hispanic or Latino,Hispanic or Latino

TIV 2010

SDY224_PBMC_TIV2010_ImmPort

23900141

US: New York

SDY269

Influenza23 (Inactivated)

28

80

TIV (2008)

None

White,Asian,Black or African American

Not Hispanic or Latino,Hispanic or Latino

TIV Group 2008

SDY269_PBMC_TIV_Geo

21743478

US: Georgia

SDY270

Influenza23 (Inactivated)

28

83

TIV (2009)

None

White,Black or African American,Asian

Not Hispanic or Latino,Hispanic or Latino

TIV Group 2009

SDY270_PBMC_TIVGroup_Geo

21743478

US: Georgia

SDY400

Influenza21 (Inactivated)

30

120

TIV (2012)

None

White,Asian,Black or African American,Other

Not Hispanic or Latino,Hispanic or Latino

Young adults 21-30 years old,Older adults >  = 65 years old

SDY400_PBMC_Young_Geo,SDY400_PBMC_Older_Geo

32060136

US: Connecticut

SDY404

Influenza25 (Inactivated)

39

156

TIV (2011)

None

White,Unknown,Other,Asian,Black or African American

Not Hispanic or Latino,Hispanic or Latino

Young adults 21-30 years old,Older adults >  = 65 years old

SDY404_PBMC_Young_Geo,SDY404_PBMC_Older_Geo

25596819

US: Connecticut

SDY520

Influenza21 (Inactivated)

24

94

TIV (2013)

None

White,Asian,Black or African American

Not Hispanic or Latino,Hispanic or Latino

Young adults 21-30 years old,Older adults >  = 65 years old

SDY520_WholeBlood_Young_geo,SDY520_WholeBlood_Older_Geo

32060136

US: Connecticut

SDY56

Influenza22 (Inactivated)

63

288

TIV (2010)

None

White,Asian,Black or African American

Not Hispanic or Latino,Hispanic or Latino

Healthy adults 25-40 years old receiving TIV flu vaccine,Healthy adults >65 years old receiving TIV flu vaccine

SDY56_PBMC_Young,SDY56_PBMC_Older

26682988

US: Georgia

SDY61

Influenza23 (Inactivated)

9

27

TIV (2007)

None

White

Not Hispanic or Latino,Hispanic or Latino

TIV Group 2007

SDY61_PBMC_TIVGrp

21743478

US: Georgia

SDY63

Influenza25 (Inactivated)

19

72

TIV (2010)

None

White,Asian,Other,Black or African American

Not Hispanic or Latino

Young adults 21-30 years old,Older adults >  = 65 years old

SDY63_PBMC_Young_Geo,SDY63_PBMC_Older_Geo

25596819

US: Connecticut

SDY640

Influenza21 (Inactivated)

20

79

TIV (2014)

None

White,Asian,Unknown

Not Hispanic or Latino,Hispanic or Latino

Young adults 21-30 years old,Older adults >  = 65 years old

SDY640_WholeBlood_Young_Geo,SDY640_WholeBlood_Older_Geo

32060136

US: Connecticut

SDY80

Influenza54 (Inactivated)

61

286

TIV (2009) + pH1N1

None

White,Asian,Other,Black or African American

Other,Hispanic or Latino

Cohort2

SDY80_PBMC_Cohort2_geo

24725414

US: Maryland

SDY269

Influenza23 (Live attenuated)

28

83

LAIV (2008)

LAIV

White,Black or African American,Asian

Not Hispanic or Latino,Hispanic or Latino

LAIV group 2008

SDY269_PBMC_LAIV_Geo

21743478

US: Georgia

SDY1293

Malaria55 (Recombinant protein)

44

165

RTS,S/AS01 or RTS,S/AS02

AS01/AS02

Not Specified

Not Specified

adjuvanted RTS,S malaria vaccine cohort

SDY1293_PBMC_Vaccinated_geo

20078211

US: Maryland

SDY1260

Meningococcus33 (Conjugate)

17

51

MCV4

None

Not Specified

Not Specified

MCV4

SDY1260_PBMC_MCV4_Geo

24336226

US: Georgia

SDY1325

Meningococcus56 (Conjugate)

5

10

MenACWY-CRM

None

Not Specified

Not Specified

Intramuscular MenACWY-CRM

SDY1325_WholeBlood_IntramuscularCRM_Geo

28137280

England

SDY1260

Meningococcus33 (Polysaccharide)

13

39

MPSV4

None

Not Specified

Not Specified

MPSV4

SDY1260_PBMC_MPSV4_Geo

24336226

US: Georgia

SDY1325

Meningococcus56 (Polysaccharide)

5

10

MenACWY-PS

None

Not Specified

Not Specified

Intramuscular MenACWY-PS

SDY1325_WholeBlood_IntramuscularPS_Geo

28137280

England

SDY180

Pneumococcus51 (Polysaccharide)

12

101

Pneumovax23

None

White,Black or African American,Asian

Not Hispanic or Latino,Hispanic or Latino

Study group 2 Pneunomax23,Study group 1 Pneunomax23

SDY180_WholeBlood_Grp2Pneunomax23_Geo,SDY180_WholeBlood_Grp1Pneunomax23_Geo

23601689

US: Texas

SDY1370

Smallpox57 (Live virus)

4

24

DryVax

Vaccinia

Unknown

Not Specified

DryVax

SDY1370_PBMC_dryvax_geo

21921208

US: Massachusetts

SDY1370

Smallpox57 (Live virus)

4

24

LC16m8

Vaccinia

Unknown

Not Specified

LC16m8

SDY1370_PBMC_lc16m8_geo

21921208

US: Massachusetts

SDY1364

Tuberculosis58 (Recombinant Viral Vector)

12

36

MVA85A

Vaccinia

Not Specified

Not Specified

MVA85A intramuscular

SDY1364_PBMC_IntraMuscular_Geo

23844129

England

SDY984

Varicella Zoster27 (Live attenuated)

72

288

Zostavax

VZV

White,Black or African American,Unknown,Asian

Not Hispanic or Latino,Hispanic or Latino

young,elderly

SDY984_PBMC_Young_Geo,SDY984_PBMC_Elderly_Geo

28502771

US: Georgia, US: Colorado

SDY1264

Yellow Fever19 (Live attenuated)

25

87

YF17D

YF17D

Not Specified

Not Specified

Trial2,Trial1

SDY1264_PBMC_Trial2_Geo,SDY1264_PBMC_Trial1_Geo

19029902

US: Georgia

SDY1289

Yellow Fever18 (Live attenuated)

25

117

YF17D

YF17D

Not Specified

Not Specified

in vivo vaccination study Montreal adult cohort,in vivo vaccination study Lausanne adult cohort

SDY1289_WholeBlood_MontrealCohort_Geo,SDY1289_WholeBlood_LausanneCohort_Geo

19047440

Canada, Switzerland, US: Georgia

SDY1294

Yellow Fever59 (Live attenuated)

21

109

YF17D

YF17D

Asian

Not Hispanic or Latino

Chinese cohort

SDY1294_PBMC_ChineseCohort_Geo

28687661

China

SDY1529

Yellow Fever18 (Live attenuated)

36

180

YF17D

YF17D

Black or African American

Not Hispanic or Latino

healthy adults

SDY1529_WholeBlood_HealthyAdults_PreVax_Geo,SDY1529_WholeBlood_HealthyAdults_PostVax_Geo

19047440

Uganda