Table 1 Cell line metadata.

From: A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations

Cell Line name

In-house name

Recived From

Tissue Location

Genetic

SURF1 Mutation

Ethnicity

Sex

Donor Age (years)

Passage

Cat #

HC1

hFB12

Lifeline Cell Technology

Dermal Breast

Normal

N/A

Caucasian

male

18

1

FC-0024 Lot # 03099

HC2

hFB13

LifeLine Cell Technology

Dermal Breast

Normal

N/A

Caucasian

female

18

1

FC-0024 Lot # 00967

HC3

hFB14

Corriel Institute

Foreskin

Normal

N/A

Black

male

0

4

AG01439

HC4

hFB11

Hirano Lab

Dermal Upper-Arm Skin

Normal

N/A

N/A

male

3

4

 

HC5

hFB1

Hirano Lab

Dermal Upper-Arm Skin

Normal

N/A

Caucasian

male

29

3

 

HC6

hFB2

Hirano Lab

Dermal Upper-Arm Skin

Normal

N/A

Caucasian

female

26

4

 

SURF1_1

hFB6

Hirano Lab

Dermal Upper-Arm Skin

SURF1 Mutation

c.518_519del (p.S173Cfs*7) c.845_846del (p.S282Cfs*7)

N/A

male

0.25

7

 

SURF1_2

hFB7

Hirano Lab

Dermal Upper-Arm Skin

SURF1 Mutation

c.247_248insCTGC (p.R83Pfx*7) c.313_321del (p.L105_A107del)

N/A

male

11

5

 

SURF1_3

hFB8

Hirano Lab

Dermal Upper-Arm Skin

SURF1 Mutation

Homozygous c.313_321del (p.L105_A107del)

N/A

female

9

9

 
  1. Demographic, tissue of origin, and genetic characteristics of the primary human fibroblast cell lines used in the Cellular Lifespan Study dataset. The dataset includes 6 healthy control donors, and 3 donors with SURF1 mutations that alter mitochondrial respiratory chain complex IV assembly and function, and lead to early death in affected patients.
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