Table 2 Dimensionality of biological measures available in this dataset.

From: A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations

Biological measures

Platform

# of parameters

# of Samples

Timepoints per cell line&

Frequency (days) *

Total data points

Cell cytology

Countess

3

1,547

Avg. 21 (7,41)

Avg. 7 (5,22)

5 × 10e3

Cell morphology

Bright field microscopy

2

1,547

Avg. 21 (7,41)

Avg. 7 (5,22)

3 × 10e3

Bioenergetics

Seahorse XFe96

34

468

Avg. 9 (3,18)

Avg. 6 (6,7)

16 × 10e3

Transcriptomics

RNAseq Illumina HiSeq

28,633

345

Avg. 8 (2,19)

Avg. 11 (5,15)

1 × 10e7

Telomere length

qPCR

1

496

Avg. 7 (2,15)

Avg. 8 (4,15)

500

DNA methylation

Illumina EPIC Bead Array

865,817

479

Avg. 7 (2,15)

Avg. 8 (4,15)

427 × 10e6

Whole Genome Sequencing

Illumina HiSeq

~3,200,000,000

94

Avg. 6 (2,11)

Avg. 18 (8,28)

301 × 10e9

IL6

ELISA

1

695

Avg. 10 (5,20)

Avg. 8 (5,15)

700

GDF15

ELISA

1

100

Avg. 9 (7,10)

Avg. 21 (10,60)

100

Cytokines

Luminex array

52

76

Avg. 8 (6,10)

Avg. 21 (10,60)

4 × 10e3

cf-mtDNA

qPCR

2

695

Avg. 12 (6,20)

Avg. 8 (5,15)

1.4 × 10e3

mtDNA copy number

qPCR

2

494

Avg. 10 (5,20)

Avg. 8 (4,15)

1 × 10e3

mtDNA sequencing

Ion Torrent

10

120

Avg. 8 (4,14)

Avg. 8 (8,8)

1.2 × 10e3

  1. Molecular, cellular and bioenergetic features, the technique or platform used to generate the data, their temporal resolution, and the dimensionality of datasets for each biological measure. &Values are averages with minimum and maximum number of timepoints (min, max). * The frequency of passaging differs by study Phase: Phase I, 5 days; Phase II, 5 days; Phase III, 7 days; Phase IV, 7 days; Phase V, 5 days.
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