Fig. 1
From: Gene expression genetics of the striatum of Diversity Outbred mice
Screenshot of a query for the gene “Rab3b” in QTL Viewer. QTL results for Rab3b expression in the Diversity Outbred (J:DO) mice striatum. Metadata related to the J:DO generation and sex is displayed, and genes co-expressed with the selected gene can be accessed from the correlation tab. The allele effect plots, SNP association mapping, and mediation analysis can also be performed and viewed from the page by click on the tab and then the QTL peak to run the analysis. Upper right: A genome scan for Rab3b expression in the Diversity Outbred (J:DO) mice striatum identifies a strong (LOD > 65) cis-eQTL on chromosome 4. Lower Right: The allele effect plot for the haplotypes of the J:DO that regulate the expression of Rab3b. There are strong effects of WSB/EiJ, NZO/HILtJ, and C57BL/6 J on the expression in one direction and 129S1/SvJ, CAST/EiJ, and A/J in the opposite direction.
