Fig. 2
From: Integrative cross-species analysis reveals conserved and unique signatures in fatty skeletal muscles
SnRNA-seq identifies distinct cell populations of aged human and high IMF content pig muscles. (a) Scheme of the experimental design for snRNA-seq on different muscle nuclei. (b) UMAP visualization of all of the isolated single nuclei from aged human and high IMF content pig muscles colored by cluster identity. (c) UMAP and violin plot displaying the expression of selected marker genes for each cluster in different species. (d) Nuclear proportion in each cluster in aged human and high IMF content pig muscles. Each cluster is color-coded. (e) Left, heatmap showing the top 10 most DEGs by bimod difference analysis algorithm (P-Value < 0.01, Log2FC ≥ 0.26) between cell types identified. Right, KEGG enrichment for marker genes of each cell type in different species. Each lane represents a subcluster.
