Fig. 3
From: Integrative cross-species analysis reveals conserved and unique signatures in fatty skeletal muscles
Inter-species comparison identifies core gene program of fat infiltration in skeletal muscle. (a) Dotplot showing the expression of preadipocyte-related genes, mature adipocyte marker genes, adipogenic master genes, and lipid metabolism-related genes in aged human muscles. (b) Dotplot showing the expression of preadipocyte-related genes, mature adipocyte marker genes, adipogenic master genes, and lipid metabolism-related genes in high IMF content pig muscles. (c) Conserved and species-specific genes of top 15 expressed genes in different cell clusters. The conserved genes among all species were marked in the left center of circles with different colors showing each cell types. Species-specific genes were located at the right rectangles with different colors showing each species. (d) The association between conserved genes in aged human muscles. (e) The association between conserved genes in high IMF content pig muscles.
