Table 3 Strategy to assign drug-target interaction types (DTI).
In DRUG_MECHANISM table? | max_phase? | Therapeutic target? | DTI annotation | Explanation |
|---|---|---|---|---|
Yes | 4 | — | D_DT | Drug – drug target |
Yes | 3 | — | C3_DT | Clinical candidate in phase 3 – drug target |
Yes | 2 | — | C2_DT | Clinical candidate in phase 2 – drug target |
Yes | 1 | — | C1_DT | Clinical candidate in phase 1 – drug target |
Yes | <1 | — | C0_DT | Compound in unknown clinical phase – drug target |
No | — | Yes | DT | Drug target |
No | — | No | NDT | Not drug target |
