Fig. 7
From: A comprehensive IDA and SWATH-DIA Lipidomics and Metabolomics dataset: SARS-CoV-2 case control study
(A) Quality control assessment of Sciex QTOF performance using selected deuterated lipids (18:1(d7) Lyso PE, 15:0-18:1(d7) DAG, 18:1(d7) Cholesterol Ester, d18:1-18:1(d9) Sphingomyelin, and 18:1(d7) Lyso PC) from the SPLASHTM Lipidomix®. The plots display the reproducibility of peak areas across all samples, including healthy control participants (nrCL) and Covid-19 patients (nrFL), ensuring consistent instrument performance and data reliability throughout the study. (B) Evaluation of LC-MS run quality, focusing on minimal carryover observed in blank samples analysed across the study. Total ion chromatograms (TIC) plots of QC samples (red lines) and blank samples (black lines) illustrate the absence of significant contamination or interference, validating the robustness of the LC-MS system for lipidomics analysis.
