Fig. 3
From: High-throughput drug screening identifies novel therapeutics for Low Grade Serous Ovarian Carcinoma
Screen outcomes across all 13 cell lines utilised in this study. (a) Number of compounds that induced cytotoxicity (robust Z-score ≤ −2) or significantly increased proliferation (robust Z-score ≥ 2). Dashed line represents median number of hits as per the indicated concentration (0.1 µM and 1 µM). (b) Waterfall plots demonstrating the proportion of compounds designated as significant by a robust Z-score cut off ≤ −2 or ≥ 2 (indicated by dashed lines) across the cell line panel at 0.1 µM and 1 µM. The percentages are calculated based on the number of compounds in the primary screen library.
