Fig. 5
From: High-throughput drug screening identifies novel therapeutics for Low Grade Serous Ovarian Carcinoma

Cell line compound sensitivity. Representative CellProfiler segmentation (top) and brightfield DAPI images of IOSE-523 (toxicity control) and LGSOC cell lines (VOA-3448, VOA-6406, VOA-10841) treated with (a) 0.2% DMSO (vehicle control) or (b) Cobimetinib, Siremadlin and Doecetaxel for 72hrs (0.1 and 1 μM). Images taken at 10X magnification. (c) Robust Z-score values for compounds depicted in (b), with values < −2 indicating cytotoxicity.