Table 1 Study demographics and image acquisition parameters of each dataset used in building in the reference curves.

From: Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI

Study/Dataset

Exclusion Criteria

Age Range (years)

Available N (% Male)

Sampled N (% Male)

Country

Manufacturer (Field Strength)

b-values (volumes)

Resolution (mm3)

PING

—

3–21

906 (52.2)

902 (52.1)

United States

Siemens (3 T)

GE (3 T)

Philips (3 T)

0 (4), 1000 (32)

0 (2), 1000 (30)

0 (3), 1000 (30)

2.5 × 2.5 × 2.5

2.5 × 2.5 × 2.5*

2.5 × 2.5 × 2.5

HCP-D

—

8–21

617 (48.5)

617 (48.5)

United States

Siemens (3 T)

0 (28), 1500 (93), 3000 (92)

1.5 × 1.5 × 1.5

ABCD

One sibling per family included

9–13

5611 (52.7)

5000 (52.8)

United States

Siemens (3 T)

0 (7), 500 (6), 1000 (15), 2000 (15), 3000 (60)

1.7 × 1.7 × 1.7

SLIM

—

17–26

432 (45.1)

432 (45.1)

China

Siemens (3 T)

0 (1), 1000 (30)

2.0 × 2.0 × 2.0

HCP

One sibling per family included

22–36

363 (45.5)

363 (45.5)

United States

Siemens (3 T)

0 (18), 1000 (90), 2000 (90), 3000 (90)

1.25 × 1.25 × 1.25

Cam-CAN

—

18–87

305 (35.1)

305 (35.1)

United Kingdom

Siemens (3 T)

0 (3), 1000 (30), 2000 (30)

2.0 × 2.0 × 2.0

PPMI

Parkinson’s disease

30–81

83 (63.9)

83 (63.9)

International

Siemens (3 T)

0 (1), 1000 (64)

1.98 × 1.98 × 2.0

UK Biobank

ICD-10 codes: C70-C72, G, I6, Q0, R90, R940, S01-S09; self-report conditions: 1081, 1086, 1266, 1267, 1397, 1434, 1437, 1491, 1626

45–82

31,986 (46.8)

5000 (47.0)

United Kingdom

Siemens (3 T)

0 (8), 1000 (50), 2000 (50)

2.0 × 2.0 × 2.0

OASIS3

Cognitive impairment

42–92

225 (48.4)

225 (48.4)

United States

Siemens (3 T)

0 (1), 1000 (64)

2.5 × 2.5 × 2.5

ADNI3

Cognitive impairment

55–95

370 (41.2)

370 (41.2)

United States Canada

Siemens (3 T)

Siemens (3 T)

GE (3 T)

GE (3 T)

Philips (3 T)

Philips (3 T)

0 (1), 1000 (30)

0 (7), 1000 (48)

0 (4), 1000 (32)

0 (6), 1000 (48)

0 (1), 1000 (32)

0 (4), 1000 (32)

2.0 × 2.0 × 2.0

2.0 × 2.0 × 2.0

2.0 × 2.0 × 2.0*

2.0 × 2.0 × 2.0*

2.0 × 2.0 × 2.0

2.0 × 2.0 × 2.0

  1. In multi-shell acquisitions, the shells used for DTI processing are indicated in bold.
  2. *Original acquisition dimensions. GE automatically zero-pads in k-space by default, so processing was performed on resampled data.
Back to article page