Fig. 5 | Scientific Data

Fig. 5

From: Multidimensional transcriptome dataset for systematic evaluation of Jakyakgamcho-tang-induced cell signatures

Fig. 5

Concordance between RNA-seq data and CMap transcriptomic profiles. Density plots show the distribution of Pearson’s correlation coefficients for pathway activity scores derived from our RNA-seq data and CMap L1000 profiles for positive control compounds in HepG2 cells: (a) trichostatin A, (b) wortmannin, and (c) vorinostat. Correlations were computed under matched treatment conditions (same drug; yellow) and unmatched conditions (different drugs; gray). Dashed vertical lines indicate the mean correlation for each group. Statistical significance of the differences in correlation distributions between matched and unmatched groups was assessed using the Wilcoxon rank-sum test.

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