Table 2 The levels of 5-HT, iron and metabolism-related proteins in CSF among control, non-fatigue and fatigue groups.

From: Serotonergic dysfunctions and abnormal iron metabolism: Relevant to mental fatigue of Parkinson disease

 

Control group (29 cases)

Non-fatigue group(59 cases)

Fatigue group(63 cases)

P1

P2

P3

Neurotransmitters

5-HT [ng/mL, median (quartile)]

10.617 (5.732~115.828)

8.934 (4.421~107.512)

5.546 (4.312~338.01)

0.094

0.000**

0.000**

Iron and metabolism-related proteins

Iron [nmol/mL, median (quartile)]

0.380 (0.263~0.612)

0.411 (0.261~0.8254)

0.632 (0.321~0.845)

0.354

0.000**

0.004**

Transferrin [ug/ml, median (quartile)]

0.079 (0.062~0.083)

0.104 (0.084~0.123)

0.192 (0.073~0.214)

0.001**

0.000**

0.003**

Lactoferrin (ug/ml, mean ± SD)

148.471 ± 65.153

138.822 ± 61.371

134.295 ± 53.764

0.231

0.114

0.614

Ferritin [ng/ml, median (quartile)]

5.291 (2.592~20.723)

5.771 (3.043~14.221)

5.854 (3.632~17.231)

0.783

0.63

0.853

  1. 5-HT = serotonin; P1: non-fatigue group vs. control group; P2: fatigue group vs. control group, P3: non-fatigue group vs. fatigue group. **P < 0.01.
Back to article page