Figure 4
Functional modules. The network nodes represent GO terms significantly enriched in enzymes linked to the lipid predictors of long MLS, and having lower dN/dS values in the long-living species compared to the short-living species. The edges represent enzymes shared between terms with line width proportional to the number of shared enzymes: from 1 to 12. Colored squares within each GO term node indicate the tissue in which these enzymes are linked to the lipid predictors of long MLS: green – liver, dark blue – muscle, light blue – kidney, magenta – heart, orange – brain cortex, brown – cerebellum. Sub-classes of the lipid predictors of long MLS linked to the enzymes in each functional group are listed next to the corresponding network module. The colors indicate the tissues where they are used as predictors of long MLS, according to the same color code as the GO terms.
