Figure 5
From: Altered Metabolic Profiles Associate with Toxicity in SOD1G93A Astrocyte-Neuron Co-Cultures
Glutamate and glutamine metabolism is perturbed by SOD1G93A expression. Concentrations of glutamine and glutamate, as well as alanine and histidine in the medium of (a) astrocyte-spinal neuron co-cultures and (b) astrocyte single cultures. Asterisks denote statistically significant differences (a) between co-culture genotypes after a two-way ANOVA followed by a Tukey HSD post hoc test or (b) between astrocyte genotypes after a Student’s t-test (*p < 0.05, **p < 0.01, ***p < 0.001). All figures show mean ± s.e.m. (n = 4–5).
