Table 2 Linear regression models showing association of CCR5 promoter haplotypes (HHC and non-HHC) and Relative Promoter Activity groups (CRPA score < 229 and CRPA score >= 229) with CD4 counts, CD8 Immune Activation, CD4 apoptosis and CD4: CD8 ratio.
Outcome | Predictor: CCR5 promoter haplotypes (HHC and non-HHC) | Predictor: RPA (RPA < 229 and RPA >= 229) | ||||||
|---|---|---|---|---|---|---|---|---|
HHC (n = 33) (mean, SD) | Non-HHC (n = 17) (mean, SD) | p-value (unadjusted) | p-value (adjusted for log-viremia) | RPA score < 229 (n = 38) (mean, SD) | RPA score >= 229 (n = 12) (mean, SD) | p-value (unadjusted) | p-value (adjusted for log-viremia) | |
CD4 | 607.39, 51.35 | 381.71, 341.49 | 0.0348 | 0.0703 | 598.58, 330.22 | 315.58, 384.08 | 0.0163 | 0.0346 |
CD8 Immune Activation | 31.86, 19.73 | 38.05, 27.26 | 0.3621 | 0.9868 | 32.26, 20.65 | 39.36, 27.86 | 0.3456 | 0.9755 |
CD4 apoptosis | 14.0, 6.41 | 17.6, 10.19 | 0.1362 | 0.2641 | 14.31, 7.25 | 18.05, 9.76 | 0.1595 | 0.3121 |
CD4: CD8 ratio | 0.7, 0.47 | 0.66, 0.51 | 0.7377 | 0.9136 | 0.72, 0.44 | 0.59, 0.59 | 0.4097 | 0.6798 |
