Figure 3
From: Specific expression of heme oxygenase-1 by myeloid cells modulates renal ischemia-reperfusion injury
Myeloid-restricted ablation of HO-1 exacerbates renal IRI. (A) Plasma creatinine levels and (B) histological scoring for tubular damage in LT (white bars) and HO-1M-KO (grey bars) mice subjected to sham surgery or 24 hours of reperfusion after renal IRI. Results are expressed as the mean ± SEM, ★p < 0.05; ★★p < 0.01. n = 7–9 for IRI groups and n = 5 for sham groups. (C) Representative sections of corticomedullary junction from sham-operated and IRI after 1 day of reperfusion in LT and HO-1M-KO mice (PAS-D stained). Magnification, x200. Scale bar, 100 μm.
