Figure 4
From: Highly-sensitive capture of circulating tumor cells using micro-ellipse filters
Percentage distribution of CTCs retained at individual stages. (A) Capture efficiencies for three different cell lines of breast (MCF-7), live (HepG2) and Hela, respectively (n = 3). CE for an 8-µm filter composed of square microposts with diameter of 20 µm for a single array. (B) Distribution obeys Gaussian distribution with mean value of 7.3 and standard derivation of 3.54. Dark gray is experimental values and gray is calculated ones. They are pretty fit. (C) Cumulative percentage distribution at various stages with 0 representing inlet and 13 as outlet. Experimental values are in black and calculated values in red (flow rate 1 ml/h). (D) Percentage distribution for tumor cells spiked in whole blood at various stages with mean value of 7.6. (E) Capture efficiencies for accurate small number of spiked MCF-7 cells in whole blood. (F) Capture efficiencies for accurate small number of spiked MCF-7 cells in lysed blood.
