Figure 1
From: Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms
Overview of co-crystal structures of aaRS enzymes from infectious disease organisms. In the current study, we have determined 6 co-crystal structures of aminoacyl tRNA synthetase (aaRS) enzymes from infectious disease organisms: CysRS from Borrelia burgdorferi (A), GluRS from B. burgdorferi (B) and Burkholderia thailandensis (C), TrpRS from Encephalitozoon cuniculi (D), HisRS from B. thailandensis (E), and LysRS from B. thailandensis (F). For sake of simplicity, only a single monomer is shown although some are biological oligomers such as HisRS which is a dimer.
