Table 2 Results from association analysis in targeted SNPs (N = 27) as compared to results obtained from genome-wide association (N = 13).

From: Variants in the host genome may inhibit tumour growth in devil facial tumours: evidence from genome-wide association

Locus

SNP

GWAS

Targeted loci

Chi-square

p-value

Chi-square

p-value

NBAS

377874_T

16.34

0.00005***

0.9441

0.33120

PAX3

2290941_C

13.48

0.00024**

10.94

0.00094**

PAX3

2253019_T

16.34

0.00006***

15.48

0.00008***

TLL1

476140_C

11.8

0.00059**

5.44

0.01968*

TLL1

635881_C

11.8

0.00059**

5.347

0.02076*

  1. *Significant at 0.05; **Significant at 0.001; ***Significant at 0.0001.
  2. See Supplementary Material, Table S1 for a full distribution of genotypes for cases and controls.
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