Figure 3 | Scientific Reports

Figure 3

From: Neural basis of negativity bias in the perception of ambiguous facial expression

Figure 3

(a) Neural basis of negativity bias in facial perception. Activation of the bilateral pgACC (peak Montreal Neurological Institute coordinates: x, y, z = 0, 46, 4; Z = 3.55, red cluster in upper panel) during “sad” versus “happy” choices in response to ambiguous faces was negatively correlated with the point of subjective equality (PSE). The Beck Hopelessness Scale (BHS) score was positively correlated with functional connectivities of the bilateral pgACC with the right dACC and right thalamus (yellow clusters in lower panel). The right pgACC (x, y, z = 8, 46, 2; Z = 4.23, blue cluster in upper panel) exhibited a significant negative correlation with the PSE in the contrast of 100% “sad” versus 100% “happy” faces. Significant clusters in the left putamen and the left orbitofrontal cortex are not displayed. (b) Sagittal section showing the bilateral pgACC activity, which was negatively correlated with the PSE in the contrast of “sad” versus “happy” choices in response to ambiguous faces. This cluster was consistent with the red cluster in (a). (c) Sagittal section showing the right pgACC activity, which was negatively correlated with the PSE in the contrast of 100% “sad” versus 100% “happy” faces. This cluster was consistent with the blue cluster in (a).

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