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Figure 1

From: Reconstruction of Large-scale Defects with a Novel Hybrid Scaffold Made from Poly(L-lactic acid)/Nanohydroxyapatite/Alendronate-loaded Chitosan Microsphere: in vitro and in vivo Studies

Figure 1

Characteristics of CM-ALs scaffolds containing different concentrations of CH/nHA-AL. (A) Morphology of CM-ALs (0%), CM-ALs (10%) and CM-ALs (20%) scaffolds under light microscopy (LM) and scanning electron microscopy (SEM); (B) Porosity of CM-ALs scaffolds with different CH/nHA-AL contents; (C) Compressive strength and modulus of CM-ALs scaffolds with different CM-ALs contents; (D) In vitro drug release assay of CM-ALs scaffolds for a period of up to 25 days using CH/nHA-AL and PLLA/nHA/AL scaffolds as control. Black arrow indicates PLLA/nHA matrix, while white arrow indicates CH/nHA-AL microsphers. *p < 0.05 vs CM-ALs (0%) scaffolds.

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