Figure 9

The effect of EM/AgNPs on re-epithelialization. Representative histological images (with H&E staining) of the length of the newly formed epidermis at days 3 and 7 post-surgery in the (A) control, (B) Vaseline gauze, (C) EM, (D) EM/PD and (E) EM/AgNPs groups. (F) Measurement of the length of the newly regenerated epidermis at day 3 post-surgery. (G) Schematic representation of the newly regenerated epidermis: the triangle represents the unwounded skin tissue, the circle represents the wound area, the pentagram represents the newly formed epidermis, the red arrow indicates border between unwounded skin tissue and wound area, the blue arrow indicates the advancing edge of newly-formed epidermis, and the yellow double-headed arrows indicate the length of the newly regenerated epidermis. The values are shown as the mean ± SD (n = 5). Scale bars: 200 μm.