Table 1 Comparison of the general characteristics between primary liver cancer cases and controls1.

From: Higher dietary intakes of choline and betaine are associated with a lower risk of primary liver cancer: a case-control study

Characteristics

PLC (n = 644)

Controls (n = 644)

P

Age (years)

54.0 (46.0, 62.0)

54.0 (46.0, 63.0)

0.734*

Male, n (%)

559 (86.8)

559 (86.8)

1.000

BMI (kg/m2)

22.6 (20.7, 24.8)

23.1 (21.2, 25.2)

0.002*

Physical activity (MET· h per day)

28.9 (25.0, 36.4)

35.7 (32.1, 39.6)

<0.001*

Education level, n (%)

<0.001*

 Primary school or below

155 (24.1)

74 (11.5)

 

 Secondary school

194 (30.1)

187 (29.0)

 

 High school or above

295 (45.8)

383 (59.5)

 

Household income (yuan/month), n (%)

<0.004*

 ≤2,000

230 (35.7)

254 (39.4)

 

 2,000–4,000

239 (37.1)

249 (38.7)

 

 4,000–6,000

67 (10.4)

69 (10.7)

 

 >6,000

81 (12.6)

65 (10.1)

 

 Other

27 (4.2)

7 (1.1)

 

Working strength, n (%)

0.001*

 Light

246 (38.2)

343 (53.3)

 

 Moderate

155 (24.1)

86 (13.4)

 

 Heavy

177 (27.5)

158 (24.5)

 

 Other

66 (10.2)

57 (8.9)

 

HBV infection, n (%)

523 (81.2)

not assessed

Smoking, n (%)

345 (53.6)

283 (43.9)

<0.001#

Alcohol user, n (%)

208 (32.3)

125(19.4)

<0.001#

Tea Drinker, n (%)

353 (54.8)

398 (61.8)

0.013#

Energy intake (kcal/d)2

1523 (1224, 1865)

1566 (1255, 1938)

0.004*

Total choline (mg/d)3

257 (208, 313)

288 (243, 343)

<0.001*

 Free choline (mg/d)3

42 (33, 52)

50 (41, 61)

<0.001*

 Phosphatidylcholine (mg/d)3

158 (122, 200)

178 (140, 220)

<0.001*

 Glycerophosphocholine (mg/d)3

26 (21, 32)

28 (23, 34)

<0.001*

 Phosphocholine (mg/d)3

11.0 (7.8, 15.9)

14.8 (11.0, 20.2)

<0.001*

 Sphingomyelin (mg/d)3

13.0 (9.5, 16.9)

13.9 (11.0, 17.3)

0.001*

Betaine (mg/d)3

77 (48, 119)

93 (63, 130)

<0.001*

Methionine (mg/d)3

1957 (1713, 2288)

1867 (1676, 2068)

<0.001*

Folate (μg/d)3

339 (292, 398)

335 (297, 377)

0.497*

  1. 1Continuous values are medians (P25, P75).
  2. 2Energy intakes exclude cooking oil.
  3. 3Energy-adjusted intake.
  4. *P values, Wilcoxon signed-rank test.
  5. #P values, McNemar’s test.
  6. Abbreviation: MET = metabolic equivalent.