Figure 4
From: Avian and human influenza virus compatible sialic acid receptors in little brown bats
Widespread binding of human pandemic H1N1 virus to LBB tissues. Confocal images show extensive binding of human H1N1 virus (A/H1N1/Virginia/2009) to little brown bat (LBB) (A) trachea, (C), lung and (E) intestine. Binding of human pandemic H1N1 virus was in accordance with the abundance of SA α2,6-Gal receptors in these tissues. Virus binding was observed predominantly in the submucosa and the hyaline cartilage of the (A) trachea, alveolar epithelial cells of the (C) lung and to lamina propria, muscularis and serosa of the (E) intestine. (B, D and F) mock treated trachea, lung and intestine respectively.
