Figure 4
From: Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol

Concentration – time profiles for 1o in plasma and brain after intraperitoneal administration to mice at a dose of 5 mg/kg (linear plots). Concentrations of 1o in plasma and brain are expressed as ng/mL and ng/g, respectively.