Table 2 Echocardiography data and hemodynamic values.

From: Female rats with severe left ventricle volume overload exhibit more cardiac hypertrophy but fewer myocardial transcriptional changes than males

Parameters

ShM (n = 11)

ShF (n = 7)

ArM (n = 7)

ArF (n = 7)

EDD, mm

9.3 ± 0.15

7.9 ± 0.08b

12.1 ± 0.52a

10.4 ± 0.2a, b

ESD, mm

4.4 ± 0.09

3.7 ± 0.08b

7.0 ± 0.45a

5.5 ± 0.19a, b

SW, mm

1.5 ± 0.03

1.3 ± 0.02b

1.5 ± 0.03

1.4 ± 0.03a, b

PW, mm

1.5 ± 0.03

1.4 ± 0.03b

1.6 ± 0.02

1.5 ± 0.02a

LV mass (echo), mg

1109 ± 51.2

724 ± 13.0b

1793 ± 148.9a

1246 ± 85.4a, b

Ind. LV mass (echo), mg/g

1.6 ± 0.08

2.1 ± 0.07b

2.7 ± 0.08a

3.7 ± 0.28a, b

RWT, unitless

0.33 ± 0.004

0.34 ± 0.006

0.26 ± 0.012a

0.28 ± 0.004a

mWS, mmHg.cm2

189 ± 1.8

169 ± 1.8

278 ± 15.0a

231 ± 5.6a, b

FS, %

53 ± 0.5

54 ± 0.6

42 ± 1.4a

47 ± 1.0a, b

% regurgitation

na

na

79 ± 4.5

79 ± 7.1

LAD, mm

6.4 ± 0.14

4.3 ± 0.12b

7.9 ± 0.37a

5.7 ± 0.17a, b

MWV, mm/s

20.9 ± 0.58

22.3 ± 0.74

18.0 ± 0.91

21.2 ± 0.80

MPI (Tei index)

0.39 ± 0.019

0.43 ± 0.018

0.52 ± 0.030a

0.52 ± 0.050a

HR, bpm

365 ± 11.0

396 ± 9.0

337 ± 12.9a

380 ± 9.3b

SV, µl

202 ± 3.0

160 ± 0.6b

409 ± 31.0a

260 ± 4.1a, b

CO, ml/min

74 ± 2.7

64 ± 3.2b

137 ± 10.3a

98 ± 2.7a, b

dP/dT+

5470 ± 475

6519 ± 465

4881 ± 354

5679 ± 707

dP/dT−

5389 ± 375

6598 ± 603

4526 ± 271

3467 ± 295a

EDP, mmHg

13.6 ± 0.68

11.3 ± 1.48

17.1 ± 1.06a

13.7 ± 1.60b

SAP, mmHg

125 ± 7.0

123 ± 5.0

131 ± 6.6

128 ± 9.6

DAP, mmHg

78 ± 3.0

75 ± 4.2

58 ± 2.9a

56 ± 5.2a

PP, mmHg

47 ± 5.3

48 ± 3.2

72 ± 4.8a

72 ± 5.0a

  1. EDD: end-diastolic diameter, ESD: end-systolic diameter, SW: septal wall thickness, PW: posterior wall, Ind: indexed, RWT: relative wall thickness, mWS: mean LV wall stress, FS: fractional shortening, LAD, left atrial diameter, MWV: LV mid-wall velocity, MPI: myocardial performance index, HR: heart rate, bpm: beats per minute, SV: stroke volume, CO: cardiac output, dP/dt+ and dP/dt−, maximal and minimal derivative of pressure/time, EDP: LV end-diastolic pressure, SAP: systolic arterial pressure, DAP: diastolic arterial pressure and PP: pulse pressure. Na: not applicable. Values are expressed as the mean ± SEM. The number of animals per group is indicated in parentheses. ap < 0.05 vs. the corresponding sham group and bp < 0.05 vs. the corresponding male group. Echocardiography measurements were obtained under inhaled isoflurane anaesthesia.
Back to article page