Table 2 Diagnostic models from the logistic regression and the ROC analysis results.

From: Serum Metabolomics Analysis Reveals a Distinct Metabolic Profile of Patients with Primary Biliary Cholangitis

 

Diagnosis models

AUC

SEa

95% CIb

YouDen index J

Sensitivity

Specificity

P1

(p1) = −12.17–3.79*log(4-hydroxyproline)

0.857

0.0373

0.771 to 0.920

0.592

57.69

88.73

P2

(p2) = 5.27–2.97* log(4-hydroxyproline) +5.35*log(3-hydroxyisovalerate)

0.905

0.0296

0.829 to 0.955

0.716

69.23

91.55

P3

(p3) = −4.02–3.72* log(4-hydroxyproline) +5.81*log(3-hydroxyisovalerate) −2.36*log(citraconate)

0.927

0.0257

0.856 to 0.970

0.725

80.77

90.14

P4

(p4) = −12.22–3.46* log(4-hydroxyproline) +6.62*log(3-hydroxyisovalerate) −2.44*log(citraconate) −3.80*log(pyruvate)

0.937

0.0227

0.868 to 0.976

0.754

69.23

92.69

  1. aStandard Error; bConfidence interval.