Figure 7

Relation of the dihedral angle patterns and helical arrangements or extensions. (a) Front view of the linearly ordered helical membrane proteins with the TM helices and loops. (b) Side view of the arrangement of three consecutive helices Hi-Hi+1-Hi+2 depending on the four different patterns of two consecutive Ω type angles, Ωi-Ωi+1. (c) Top view configuration of four consecutive helices, Hi-Hi+1-Hi+2-Hi+3, for the four different patterns of two consecutive λ type angles, λi-λi+1. Figure 7(a) and (b) were generated as follows. (1) The dihedral angles were computed by the original definition in the Fig. 2, (2) arrangement of helices was predicted based on the dihedral angles, and then (3) the predicted arrangement was drawn based on side view and top position. Zig-zag conformation denotes the helices are arranged or extended in the alternative direction as depicted in ++ and −− configurations.