Figure 2
From: Double-stranded DNA induces a prothrombotic phenotype in the vascular endothelium
Double-stranded DNA induces expression of prothrombotic genes in vascular endothelial cells. (a,b) Expression of the prothrombotic molecules tissue factor (a) and Plasminogen activator inhibitor-1 (PAI-1, b) as assessed by RT-PCR upon transfection of vascular endothelial cells with poly(dA:dT). (c,d) Expression of the antithrombotic molecules tissue plasminogen activator (tPA, (c)) and thrombomodulin (THBD, (d)) upon transfection of vascular endothelial cells with poly(dA:dT); (*P < 0.05 vs. respective time-matched control, n = 4).
