Table 3 Association analysis between individual SNPs and ASP risk.
SNP | Variables | Cases (%) | Controls (%) | OR (95% CI) | P | FDR_BH adjusted |
|---|---|---|---|---|---|---|
rs12778366 | TT | 193 (73.9) | 251 (76.8) | 1 | ||
TC | 65 (24.9) | 67 (20.5) | 1.26 (0.86–1.86) | 0.242 | ||
CC | 3 (1.1) | 9 (2.8) | 0.43 (0.12–1.62) | 0.215 | 0.426 | |
Dom. | 1.16 (0.80–1.70) | 0.431 | 0.431 | |||
Rec. | 0.41 (0.11–1.53) | 0.186 | 0.371 | |||
Add. | 1.05 (0.75–1.47) | 0.764 | 0.764 | |||
rs7896005 | AA | 178 (68.2) | 243 (74.3) | 1 | ||
AG | 77 (29.5) | 77 (23.5) | 1.37 (0.94–1.98) | 0.099 | ||
GG | 6 (2.3) | 7 (2.1) | 1.17 (0.39–3.54) | 0.781 | 0.781 | |
Dom. | 1.35 (0.94–1.93) | 0.103 | 0.193 | |||
Rec. | 1.08 (0.36–3.24) | 0.897 | 0.897 | |||
Add. | 1.28 (0.93–1.76) | 0.137 | 0.182 | |||
rs10823112 | AA | 133 (51.0) | 191 (58.4) | 1 | ||
AG | 106 (40.6) | 113 (34.6) | 1.35 (0.95–1.90) | 0.091 | ||
GG | 22 (8.4) | 23 (7.0) | 1.37 (0.74–2.57) | 0.953 | 0.426 | |
Dom. | 1.35 (0.97–1.88) | 0.071 | 0.193 | |||
Rec. | 1.22 (0.66–2.24) | 0.528 | 0.704 | |||
Add. | 1.25 (0.96–1.61) | 0.094 | 0.182 | |||
rs4746720 | TT | 88 (33.7) | 92 (28.1) | 1 | ||
CT | 134 (51.3) | 151 (46.2) | 0.93 (0.64–1.35) | 0.694 | ||
CC | 39 (14.9) | 84 (25.7) | 0.49 (0.30–0.78) | 0.003 | 0.012 | |
Dom. | 0.77 (0.54–1.09) | 0.145 | 0.193 | |||
Rec. | 0.51 (0.33–0.77) | 0.002 | 0.007 | |||
Add. | 0.72 (0.57–0.91) | 0.006 | 0.024 |
