Table 5 Pairwise interactions between genetic variants of rs4746720.

From: Possible association between SIRT1 single nucleotide polymorphisms and predisposition to antisocial personality traits in Chinese adolescents

Variables

OR (95%CI)a

OR (95%CI)b

OR (95%CI)b

OR (95%CI)b

CT + TT

CC

Variables

rs4746720

Interaction

Tobacco smoking

  

23.57 (14.22–39.07) ***

1.64 (0.24–10.95)

0.54 (0.22–1.37)

never

Ref.

0.71 (0.20–2.65)

   

sometimes

Ref.

0.66 (0.23–1.90)

   

Often

Ref.

0.21 (0.05–0.84)

   

Alcohol consumption

  

4.69 (3.21–6.85)***

2.64 (0.56–12.53)

0.43 (0.20–0.94)*

never

Ref.

1.15 (0.49–2.69)

   

sometimes

Ref.

0.44 (0.25–0.77)

   

Often

Ref.

0.09 (0.01–0.62)

   

Network usage

  

1.81 (1.33–2.46)***

0.39 (0.04–3.76)

1.07 (0.46–2.47)

never

Ref.

0.40 (0.24–0.68)

   

sometimes

Ref.

0.78 (0.33–1.84)

   

Often

Ref.

0.40 (0.24–0.68)

   

Emotional abuse

  

15.38 (8.54–27.70)***

0.48(0.27–0.84)*

2.02 (0.48–8.53)

none to moderate

Ref.

0.48 (0.27–0.84)

   

moderate to extreme

Ref.

0.97 (0.26–3.65)

   

Physical abuse

  

21.15 (10.31–43.37)***

0.49 (0.28–0.83)**

1.68 (0.31–9.21)

none to moderate

Ref.

0.49 (0.28–0.84)

   

moderate to extreme

Ref.

0.81 (0.16–4.10)

   

Sex abuse

  

24.48 (11.01–54.43)***

0.45 (0.26–0.76)**

1.47 (0.26–8.34)

none to moderate

Ref.

0.32 (0.14–0.73)

   

moderate to extreme

Ref.

0.52 (0.21–1.28)

   

Emotional neglect

  

7.02 (4.48–10.98)***

0.66 (0.38–1.14)

0.55 (0.21–1.44)

none to moderate

Ref.

0.66 (0.38–1.14)

   

moderate to extreme

Ref.

0.37 (0.17–0.80)

   

Physical neglect

  

7.93 (5.05–12.45)***

0.55 (0.30–1.00)

0.58 (0.23–1.47)

none to moderate

Ref.

0.55 (0.30–0.99)

   

moderate to extreme

Ref.

0.32 (0.16–0.65)

   
  1. aData calculated by univariate logistic regression; bData calculated by multivariate logistic regression (Y = a0 + a1 X1 + a2 X2 + a1a2 X1 * X2); Positive results are in bold. *P < 0.05 (two-tailed), **P < 0.01 (two-tailed), ***P < 0.001 (two-tailed).